Eosinophilic Esophagitis (EoE)

Eosinophilic esophagitis (e-o-sin-o-FILL-ik uh-sof-uh-JIE-tis) is a build-up of white blood cells (eosinophils) in the lining of the tube that connects your mouth to your stomach. The disease is becoming more common, similar to the increase in people affected by asthma and allergies. As an inflammation, it can be painful and often manifests itself with symptoms such as:

  • head-neck-illustrationStomach ache
  • Difficulty swallowing
  • Gastroesophageal reflux disease (GERD) symptoms that don’t respond to medication:
    • Heartburn
    • Burping
    • Vomiting
  • Chronic cough
  • Poor weight gain in children
  • Anemia

It can also be associated with underlying conditions such as allergies.

In more than half of pediatric cases of eosinophilic esophagitis, allergies are the major cause. When allergies are identified, their treatment may lead to dramatic improvement in eosinophilic esophagitis and even its resolution.

Foods that are commonly found to be responsible for eosinophilic esophagitis may include milk, wheat, corn, but other foods may also contribute.

Sublingual immunotherapy for eosinophilic esophagitis addresses both inhalant and food allergies and is especially beneficial for children with eosinophilic esophagitis because of its safety profile and increased compliance. Eosinophilic esophagitis in children is likely to be associated with conditions such as asthma, nasal polyps and chronic sinusitis, which can be avoided with early diagnosis and immunotherapy treatment.