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Research Supporting Sublingual Immunotherapy

Attention physicians! Isn't it time you learn how you can help your patients treat the root cause of their allergy?
Millions of people across the globe suffer from allergies, asthma, and other related immunologic disease. Though clinical practice of sublingual immunotherapy in the U.S. dates back nearly 100 years, sublingual immunotherapy research validating what was learned clinically has only begun to garner attention in the past few decades.

  • Bibliography — modern research references for sublingual immunotherapy, including recent findings through the Agency for Healthcare Research & Quality (AHRQ), World Health Organization, and Cochrane Collaboration
  • Supporting Evidence — studies that specifically address the key tenets of the La Crosse Method™ Protocol
  • La Crosse Method Protocol Author Research

A large number of controlled clinical trials in Europe have shown the effectiveness of sublingual immunotherapy in the treatment of allergic rhinitis and asthma for single antigens. More studies are underway in the U.S. and globally, including studies that explore food allergies. Additional research has shed light on the mechanisms behind sublingual immunotherapy, notably the unique role dendritic cells under the tongue play in building allergen tolerance.