The La Crosse Method Difference

Not all forms of sublingual immunotherapy are the same.

At Allergychoices, we advocate the La Crosse Method™ Protocol because it offers a comprehensive, safe, and effective approach to treat a broad range of allergic conditions.

In use since 1970, this treatment protocol has been used to help more than 275,000 people live healthier, happier lives. In addition, Protocol authors participate in research studies and keep up on the latest available research literature. We have helped train thousands of physicians around the country using this Protocol.

Learn how allergy drops compare to sublingual tablets →

The Allergic Fingerprint


Your fingerprint is complex, comprehensive, and entirely unique to you. Your allergies are, too.

When diagnosing a patient through the La Crosse Method Protocol, your “allergic fingerprint” is identified through a thorough exam, history, and testing. Based on the outcome, your provider develops your treatment based on your specific level of sensitivity to the precise items that cause your reactions.

Allergy drops are customized to your needs in an optimal dose that allows you to build tolerance, and because they are unique to you, there’s a better margin of safety. It provides enough antigen to help you build tolerance, but not enough to cause an unnecessary reaction. It’s not a one size fits all approach.

And since the majority of patients have more than one allergy, patients receive treatment for multiple allergies at once. We use a glycerin preservative base that keeps antigens stable at room temperature. As your allergy treatment journey progresses, we work with your provider to formulate stronger doses as your tolerance builds to individual allergens. It’s a personalized treatment approach with your allergic fingerprint at the forefront.

Dose Amounts

The La Crosse Method focuses on the specific allergen dose for your unique allergic fingerprint. Your specific test results, along with medical history and exam, are used to create a custom allergy drop dose for you — high enough to be effective, but not unnecessarily high to increase risk of reactions or expense. Just as no two patients, and no two fingerprints, are identical, your dose is optimized to create an effective dose uniquely for you.

Dose Frequency

Research on medication adherence has shown that frequency and consistency is the key to improving symptoms. Taking three doses a day keeps tolerance-building cells stimulated and reduces the risk of reactions from less frequent, higher doses. Spreading doses throughout the day, or taking one in the morning and two at night, could improve effectiveness even more.

Dose Simplicity

The La Crosse Method offers the simplicity of consistent patient instructions throughout treatment. Patients follow consistent dosing instructions and are prescribed one bottle for specific environmental or food allergies. Each prescription contains a 90-day treatment supply which is adjusted in strength throughout treatment as you build tolerance.